| Identification | Back Directory | [Name]
Pyrido[3,2-g]quinoline-2,5,8,10(1H,9H)-tetrone, 1,4,6,9-tetramethyl- | [CAS]
637772-75-9 | [Synonyms]
SCH 538415 SCH-538415 SCH 538415,SCH538415 Pyrido[3,2-g]quinoline-2,5,8,10(1H,9H)-tetrone, 1,4,6,9-tetramethyl- | [Molecular Formula]
C16H14N2O4 | [MOL File]
637772-75-9.mol | [Molecular Weight]
298.29 |
| Hazard Information | Back Directory | [Uses]
SCH-538415 is a novel acyl carrier protein synthase inhibitor isolated from an unknown bacterial microorganism. The structural elucidation of compound 1 was completed by analyzing spectral data including UV, MS and 2D-NMR spectra. Compound 1 showed inhibitory activity in the acyl carrier protein synthase (AcpS) test with an IC50 value of 4.19 μM and exhibited antibacterial activity against Staphylococcus aureus in the agar diffusion test. | [References]
[1] Structure elucidation of Sch 538415, a novel acyl carrier protein synthase inhibitor from a microorganism |
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