| Identification | More | [Name]
Phenethylamine | [CAS]
64-04-0 | [Synonyms]
1-AMINO-2-PHENYLETHANE
2-AMINOETHYLBENZENE
2-PHENETHYLAMINE
2-PHENYLETHYLAMINE
3-AMINOETHYLBENZENE
AKOS BBS-00003597
AURORA KA-7805
B-AMINOETHYLBENZENE
BENZENEETHANAMINE
(BETA-AMINOETHYL)-BENZENE
BETA-PHENETHYLAMINE
BETA-PHENYLETHYLAMINE
B-PHENYLETHYLAMINE
FEMA 3220
LABOTEST-BB LTBB000487
PHEA
PHENETHYLAMINE
RARECHEM AL BW 0047
1-Phenyl-2-amino-athan
1-Phenyl-2-aminoethane | [EINECS(EC#)]
200-574-4 | [Molecular Formula]
C8H11N | [MDL Number]
MFCD00008184 | [Molecular Weight]
121.18 | [MOL File]
64-04-0.mol |
| Chemical Properties | Back Directory | [Appearance]
colourless or slightly yellow liquid with | [Melting point ]
-60 °C
| [Boiling point ]
197-200 °C (lit.) | [density ]
0.962 g/mL at 20 °C(lit.)
| [vapor density ]
4.18 (vs air)
| [vapor pressure ]
0.4 hPa (20 °C) | [FEMA ]
3220 | [refractive index ]
n20/D 1.533(lit.)
| [Fp ]
195 °F
| [storage temp. ]
2-8°C
| [solubility ]
alcohol: freely soluble(lit.) | [form ]
liquid
| [pka]
9.84(at 25℃) | [color ]
clear, colorless
| [Odor]
fishy odor | [PH]
11.5 (4.3g/l, H2O, 20℃) | [PH Range]
11.5 at 4.3 g/l at 20 °C | [Stability:]
Stable. Combustible. Incompatible with strong oxidizing agents, strong acids. | [explosive limit]
1.0-5.5%(V) | [Odor Type]
fishy | [Water Solubility ]
SOLUBLE | [Sensitive ]
Air Sensitive | [Detection Methods]
GC,NMR | [JECFA Number]
1589 | [Merck ]
14,7225 | [BRN ]
507488 | [InChIKey]
BHHGXPLMPWCGHP-UHFFFAOYSA-N | [LogP]
1.46 | [CAS DataBase Reference]
64-04-0(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzeneethanamine(64-04-0) | [Storage Precautions]
Air sensitive | [EPA Substance Registry System]
Phenethylamine (64-04-0) |
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R22:Harmful if swallowed.
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2922 8/PG 2
| [WGK Germany ]
1
| [RTECS ]
SG8750000
| [F ]
9-23 | [Autoignition Temperature]
425 °C | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29214980 | [Safety Profile]
Poison by intraperitoneal, subcutaneous, intracervical, and intravenous routes. Moderately toxic by ingestion. A strong base. A skin irritant and possible sensitizer. When heated to decomposition it emits toxic fumes of NOx. See also AMINES | [Hazardous Substances Data]
64-04-0(Hazardous Substances Data) | [Toxicity]
LD50 orally in Rabbit: 300 mg/kg |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
Ammonia-->Nickel | [Preparation Products]
2-(PIPERAZIN-1-YL)-ACETIC ACID N-(2-PHENYLETHYL)-AMIDE-->1,2,3,4-TETRAHYDROISOQUINOLINE-->FLUCYTHRINATE-->N-BENZYL-2-PHENYLETHYLAMINE-->7-Aminoisoquinoline-->7-NITRO-3,4-DIHYDROISOQUINOLINE-->3,4-DIHYDROISOQUINOLINE-->2-(2-NITROPHENYL)ETHANAMINE-->Glipizide-->4-NITRO-PHENETHYLAMINE-->Triethyl 1,3,5-benzenetricarboxylate-->2-CYCLOHEXYL-ETHYLAMINE HYDROCHLORIDE-->2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINE-->7-AMINO-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE-->2-Aminoecetophenone |
| Hazard Information | Back Directory | [Chemical Properties]
colourless or slightly yellow liquid with | [Chemical Properties]
Phenethylamine has a fish odor. | [Occurrence]
Reported found in the oil of bitter almonds. Also found in grapes, cabbage, kale, carrots, blue and provolone
cheese, fatty fish, beer, sherry, grape wines, cocoa, cauliflower, beetroot, radish, rhubarb, sake and dried bonito. | [Uses]
Phenethylamine is used in manufacturing anti-depression agents and anti diabetic drugs. It is also used as the goodds for drug jiangtangling intermediate, also used for other organic synthesis. | [Definition]
ChEBI: A phenylethylamine having the phenyl substituent at the 2-position. | [Preparation]
By reduction of benzyl cyanide with sodium metal in alcohol or with Raney-Ni. | [Synthesis Reference(s)]
Chemical and Pharmaceutical Bulletin, 34, p. 3905, 1986 DOI: 10.1248/cpb.34.3905
Journal of the American Chemical Society, 94, p. 6561, 1972 DOI: 10.1021/ja00773a060
Tetrahedron Letters, 21, p. 1719, 1980 DOI: 10.1016/S0040-4039(00)77819-1 | [General Description]
Phenethylamine, a new stimulant designer drug, was analyzed by the liquid chromatography high-resolution mass spectrometry quadrupole-time-of-flight (LC-HRMS-QTOF) method. | [Purification Methods]
Distil the amine from CaH2, under reduced pressure, just before use. [Beilstein 12 H 1096, 12 IV 2453.] |
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