| Identification | Back Directory | [Name]
6-BROMO-3-NITROIMIDAZO[1,2-A]PYRIDINE | [CAS]
64064-71-7 | [Synonyms]
6-BROMO-3-NITROIMIDAZO[1,2-A]PYRIDINE
IMidazo[1,2-a]pyridine, 6-broMo-3-nitro- | [Molecular Formula]
C7H4BrN3O2 | [MDL Number]
MFCD09864963 | [MOL File]
64064-71-7.mol | [Molecular Weight]
242.03 |
| Chemical Properties | Back Directory | [density ]
1.98±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
-0.28±0.50(Predicted) | [Appearance]
Light yellow to yellow Solid |
| Hazard Information | Back Directory | [Synthesis]
GENERAL STEPS: 6-Bromoimidazo[1,2-a]pyridine (100 mg, 0.508 mmol) was dissolved in concentrated H2SO4 (0.4 mL) and concentrated HNO3 (0.12 mL, 2.69 mmol) was slowly added at room temperature. The reaction mixture was stirred for 15 min and then the reaction was quenched by the addition of ice water. The resulting solid (123 mg, 99% yield) was collected by filtration and used for subsequent reactions without further purification. The product was characterized by 1H NMR (500 MHz, DMSO-d6): δ 9.40 (t, J = 1.4 Hz, 1H), 8.78 (s, 1H), 8.00-7.85 (m, 2H); mass spectrometry (ESI) showed that the [M + H]+ peaks were located at 242.1/244.1. | [References]
[1] Patent: WO2017/66876, 2017, A1. Location in patent: Page/Page column 66
[2] Patent: US4105767, 1978, A
[3] Patent: US4177274, 1979, A
[4] Patent: US4237300, 1980, A
[5] Patent: US4096264, 1978, A |
|
| Company Name: |
SynAsst Chemical.
|
| Tel: |
021-60343070 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15848/0_EN.htm |
|