ChemicalBook--->CAS DataBase List--->640725-74-2

640725-74-2

640725-74-2 Structure

640725-74-2 Structure
IdentificationBack Directory
[Name]

2-AMino-6-chloro-9-(2-C-Methyl-β-D-ribofuranosyl)-9H-purine
[CAS]

640725-74-2
[Synonyms]

2-AMino-6-chloro-9-(2-C-Methyl-β-D-ribofuranosyl)-9H-purine
2-Amino-6-chloro-9-(2-C-methyl-β-D-ribofuranosyl)-9H-purine
9H-Purin-2-amine, 6-chloro-9-(2-C-methyl-β-D-ribofuranosyl)-
6-Chloro-9-(2-C-methyl-beta-D-ribofuranosyl)-9H-purin-2-amine
2-amino-6-chloro-9-(2-C-methyl-Beta-D-ribofuranosyl)-9H-purine
2-Amino -6-chloro-9-(2-b-C-methyl-β-D-ribofuranosyl)-9H-purine
(2R,3R,4R,5R)-2-(2-AMINO-6-CHLORO-9H-PURIN-9-YL)-5-(HYDROXYMETHYL)-3-METHYLTETRAHYDROFURAN-3,4-DIOL
[Molecular Formula]

C11H14ClN5O4
[MDL Number]

MFCD23703809
[MOL File]

640725-74-2.mol
[Molecular Weight]

315.71
Chemical PropertiesBack Directory
[Boiling point ]

695.3±65.0 °C(Predicted)
[density ]

1.99±0.1 g/cm3(Predicted)
[pka]

13.11±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

2-Amino -6-chloro-9-(2-β-C-methyl-β-D-ribofuranosyl)-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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