ChemicalBook--->CAS DataBase List--->64218-02-6

64218-02-6

64218-02-6 Structure

64218-02-6 Structure
IdentificationBack Directory
[Name]

plaunotol
[CAS]

64218-02-6
[Synonyms]

CS-684
Kelnac
Kelnal
Plegarol
PLAUNOTOL
Plaugenol
Plaunotoi
Plaunotolum
Plaunotol/CS-684
2,6-OCTADIENE-1,8-DIOL,2-[(3E)-4,8-DIMETHYL-3,7-NONADIENYL]-6-METHYL
(E,Z,E)-7-Hydroxymethyl-3,11,15-trimethyl-2,6,10,14-hexadecatetraen-1-ol
(2E,6Z,10E)-7-Hydroxymethyl-3,11,15-trimethyl-2,6,10,14-hexadecatetren-1-ol
(2Z,6E)-2-[(3E)-4,8-Dimethyl-3,7-nonadienyl]-6-methyl-2,6-octadiene-1,8-diol
2,6-OCTADIENE-1,8-DIOL, 2-[(3E)-4,8-DIMETHYL-3,7-NONADIENYL]-6-METHYL-, (2Z,6E)-
2,6-Octadiene-1,8-diol, 2-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-6-methyl-, (2Z,6E)-
[Molecular Formula]

C20H34O2
[MDL Number]

MFCD00866883
[MOL File]

64218-02-6.mol
[Molecular Weight]

306.48
Chemical PropertiesBack Directory
[Boiling point ]

440.4±45.0 °C(Predicted)
[density ]

0.936±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[pka]

14.40±0.10(Predicted)
Hazard InformationBack Directory
[Description]

Plaunotol is a diterpene alcohol extracted from the Thai plant, plau-noi. teprenone (2), it is reportedly useful as a cytoprotective anti-ulcer agent.
[Chemical Properties]

Pale yellow oil with a fragrant, bitter taste. Soluble in benzene, acetone, alcohol, or ether, but insoluble in water. Acute toxicity LD50 for male and female mice and male and female rats (μl/kg, 1 μl equivalent to 0.95 mg of refined oil): 8800, 8180, 10900, and 11200 for oral administration; 35500, 44000, 29500, and 35000 for subcutaneous injection.
[Originator]

Sankyo (Japan)
[Uses]

Plaunotol is a cytoprotective antiulcer agent that showed antibacterial activity against Helicobacter pylori and Staphylococcus aureus bacteria. It also enhanced the antibacterial activity of amoxycillin or clarithromycin antibiotics.
[Definition]

ChEBI: A diterpenoid that is geranylgeraniol carrying an additional hydroxy substituent at position 18.
[Brand name]

Kelnac
Safety DataBack Directory
[Toxicity]

LD50 in male, female mice, rats (ml/kg): 8800, 8100, 10900, 11200 orally (Kobayashi)
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106-28-5

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