| Identification | Back Directory | [Name]
AMITRIPTYLINE METABOLITE (+/-)- | [CAS]
64520-05-4 | [Synonyms]
10-Hydroxy (E)-Amitriptyline
AMITRIPTYLINE METABOLITE (+/-)-
AMITRIPTYLINE METABOLITE (+-)-(E)-10-HYD ROXYLA
Amitriptyline metabolite, (±)-E-10-hydroxylated-
(E)-5-(3-(Dimethylamino)propylidene)-10,11-dihydro-5H-dibenzo[a,d][7]annulen-10-ol
5H-Dibenzo[a,d]cyclohepten-10-ol, 5-[3-(dimethylamino)propylidene]-10,11-dihydro-, (5E)-
(11E)-11-[3-(dimethylamino)propylidene]-5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-5-ol | [Molecular Formula]
C20H23NO | [MDL Number]
MFCD00069200 | [MOL File]
64520-05-4.mol | [Molecular Weight]
293.4 |
| Hazard Information | Back Directory | [Uses]
(5E)-5-[3-(dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol is a metabolite of amitriptyline (A633350) which is a dibenzocycloheptadiene derivative and an antidepressant (1). Amitriptyline is also a TrkA and TrkB receptor agonist and exhibits neurotrophic and anti-inflammatory activities (2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). | [Definition]
ChEBI: E-10-Hydroxyamitriptyline is an organic tricyclic compound. | [Biochem/physiol Actions]
Metabolite of amitriptyline, tricyclic antidepressant; chromatographic standard. |
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