| Identification | Back Directory | [Name]
MPP A | [CAS]
6453-67-4 | [Synonyms]
MPP A
PMPCA
INPP5E
KIAA0123
Nsc267052
Chlorophyll Impurity 5
Methyl pyropheophorbide a
Methyl pyrophaeophorbide a
Methyl carbamic pyrophyllate a
PYROPHEOPHORBIDE A METHYL ESTER
Pyropheophorbide α Methyl Ester
Pyropheophorbide-alpha methyl ester
Methyl-13-decarboxy-methyl phaeophorbide-a
ANTI-PMPCA (C-TERM) antibody produced in rabbit
Mitochondrial-processing peptidase subunit alpha
9-Ethenyl-14-ethyl-4,8,13,18-tetramethyl-20-oxophorbine-3-propanoi
9-Ethenyl-14-ethyl-4,8,13,18-tetramethyl-20-oxophorbine-3-propanoicacid meth
3-Phorbinepropionic acid, 14-ethyl-4,8,13,18-tetramethyl-20-oxo-9-vinyl-, methyl ester
3-Phorbinepropanoic acid, 9-ethenyl-14-ethyl-4,8,13,18-tetramethyl-20-oxo-, methyl ester, (3S,4S)-
3-Phorbinepropanoic acid, 9-ethenyl-14-ethyl-4,8,13,18-tetramethyl-20-oxo-, methyl ester, (3S-trans)- | [Molecular Formula]
C34H36N4O3 | [MDL Number]
MFCD00057989 | [MOL File]
6453-67-4.mol | [Molecular Weight]
548.67 |
| Chemical Properties | Back Directory | [Boiling point ]
937.4±65.0 °C(Predicted) | [density ]
1.219±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
Chloroform (Slightly), Methanol (Slightly, Heated) | [form ]
Solid | [color ]
Black | [Stability:]
Light Sensitive | [InChIKey]
RYLBYBPLWNFWPG-CMMLGHQLSA-N | [SMILES]
CCc1c(C)c2cc3[nH]c(cc4nc([C@@H](CCC(=O)OC)[C@@H]4C)c5CC(=O)c6c(C)c(cc1n2)[nH]c56)c(C)c3C=C |
| Hazard Information | Back Directory | [Uses]
Pyropheophorbide A Methyl Ester is a chlorophyll (C379815) analog for studies of photosynthesis. Methyl pyropheophorbide a (Pyropheophorbide-a methyl ester), a chlorophyll-a derivative, and is a potent photosensitizer that can be used in photodynamic therapy (PDT) of cancer. Methyl pyropheophorbide a has photodynamic activity and can induce apoptosis and inhibit tumor growth. | [in vivo]
Pyropheophorbide-a methyl ester (15 mg/kg; tail vein and topical injection) inhibits the growth of PC-3M tumors in mice[2]. | Animal Model: | Male BALB/c nude mice (6-8 weeks, 16-20 g) bearing PC-3M tumor[2] | | Dosage: | 15 mg/kg | | Administration: | Tail vein injection and topical injection | | Result: | The tumor volume and the weight inhibition rate were 46.78%, 41.84% in tail vein injection group and 78.66%, 72.07% in topical injection group, respectively. |
|
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|