| Chemical Properties | Back Directory | [density ]
1.42±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
3.39±0.10(Predicted) | [color ]
White to off-white | [Sequence]
Pro-Val-Ser-Lys-Met-Arg-Met-Ala-Thr-Pro-Leu-Leu-Met-Gln-Ala |
| Hazard Information | Back Directory | [Uses]
CLIP (86-100) is amino acids 86 to 100 fragment of class II-associated invariant chain peptide (CLIP). CLIP is a small self-peptide and cleavage product of the invariant chain that resides in the HLA-II antigen binding groove and is believed to play a critical role in the assembly and transport of MHC class II alphabetaIi complexes through its interaction with the class II peptide-binding site[1]. | [References]
[1] van Luijn MM, et al. Class II-associated invariant chain peptide as predictive immune marker in minimal residual disease in acute myeloid leukemia. Oncoimmunology. 2015 Jan 7;3(12):e941737. eCollection 2014 Dec. DOI:10.4161/21624011.2014.941737
[2] Thayer WP, et al. Class II-associated invariant chain peptide-independent binding of invariant chain to class II MHC molecules. J Immunol. 1999 Feb 1;162(3):1502-9. PMID:9973407 |
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| Company Name: |
Ontores Biotech
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| Tel: |
0571-88760729 18072970094 |
| Website: |
www.ontoresinc.cn |
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