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65005-57-4

65005-57-4 Structure

65005-57-4 Structure
IdentificationBack Directory
[Name]

NG,NG'-DIMETHYL-L-ARGININE, DIHYDROCHLORIDE
[CAS]

65005-57-4
[Synonyms]

SDMA, 2HCL
NG,NG-DIMETHYLARGININE HYDROCHLORIDE
ADMA, ASYM-DIMETHYLARGININE HYDROCHLORIDE
NG,NG'-DIMETHYL-L-ARGININE, DIHYDROCHLORIDE
N(sup G),N(sup G)-dimethylarginine hydrochloride
[Molecular Formula]

C8H20Cl2N4O2
[MDL Number]

MFCD00270858
[MOL File]

65005-57-4.mol
[Molecular Weight]

275.18
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Asymmetric dimethylarginine-d7 (hydrochloride) is the deuterium labeled Asymmetric dimethylarginine hydrochloride[1].
[Definition]

ChEBI: N(omega),N(omega)-dimethyl-L-arginine is a L-arginine derivative having two methyl groups both attached to the primary amino moiety of the guanidino group. It has a role as an EC 1.14.13.39 (nitric oxide synthase) inhibitor. It is a non-proteinogenic L-alpha-amino acid, a member of guanidines, a L-arginine derivative and a dimethylarginine. It is a conjugate base of a N(omega),N(omega)-dimethyl-L-argininium(1+).
[References]

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
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