| Safety Data | Back Directory | [RIDADR ]
3249 | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [Toxicity]
LD50 in mice (mg/kg): 47 i.v. (Tachikawa) |
| Hazard Information | Back Directory | [Description]
Indeloxazine hydrochloride is a nootropic indicated for the treatment of senile dementia.
In animal models indeloxazine reportedly enhances brain energy metabolism and
monoamine content; its claimed protective effect on ischemia-induced amnesia is
supported by the prolonged step-through latency in passive avoidance tests. | [Originator]
Yamanouchi (Japan) | [Uses]
Antidepressant. | [Brand name]
Elen | [Metabolic pathway]
After oral administration of indeloxazine hydrochloride
to rats, two conjugates, which are labile to a-
glucosidase hydrolysis but refractory to b-glucosidase,
are isolated from the urine and identified as a-D-
glucopyranosides of trans-4-(2-morpholinylmethoxy)-
1,2-indandiol and trans-6-[[(1,2-dihydroxy-4-
indanyl)oxy]-methyl]-3-morpholinone. |
|
| Company Name: |
LGM Pharma
|
| Tel: |
1-(800)-881-8210 |
| Website: |
www.lgmpharma.com |
| Company Name: |
Candia Thamtech Company Limited
|
| Tel: |
0371-86615086 18203638366 0371-86159066 13526786601 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15771/0_EN.htm |
|