| Identification | Back Directory | [Name]
MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE | [CAS]
65144-34-5 | [Synonyms]
SPCK
HLE INHIBITOR
MEOSUC-APPV-CMK
MEOSUC-AAPV-CMK
ELASTASE INHIBITOR III
Elastase Inhibitor, SPCK
MEOSUC-ALA-ALA-PRO-VAL-CMK
N-(METHOXYSUCCINYL)-L-ALA-L-ALA-L-PROL.&
MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE
methoxysuccinyl-Ala-Ala-Pro-Val chloromethyl ketone
N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL*CHLORO METHYL KETO
N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL CHLOROMETHYL KETONE
N(methoxysuccinyl)-L-alanyl-L-alanyl-L-prolyl-L-valine CMK
N-(methoxysuccinyl)-L-ala-L-ala-L-prol.-L-val-chlorome.ket.
methoxysuccinyl-alanyl-alanyl-prolyl-valinechloromethylketone
N-(METHOXYSUCCINYL)-L-ALANYL-L-ALANYL-L-PROLYL-L-VALINE CHLOROMETHYLKETONE
L-Prolinamide, N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-N-[(1S)-3-chloro-1-(1-methylethyl)-2-oxopropyl]-
methyl 4-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(3S)-1-chloro-4-methyl-2-oxopentan-3-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoate | [Molecular Formula]
C22H35ClN4O7 | [MDL Number]
MFCD00077136 | [MOL File]
65144-34-5.mol | [Molecular Weight]
502.99 |
| Chemical Properties | Back Directory | [Melting point ]
159-161 °C | [Boiling point ]
809.4±65.0 °C(Predicted) | [density ]
1.234±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
ethanol: 50 mg/mL, clear, colorless | [form ]
Solid | [pka]
13.05±0.20(Predicted) | [Sensitive ]
Moisture Sensitive | [BRN ]
6167019 |
| Hazard Information | Back Directory | [Uses]
A potent irreversible inhibitor of human leukocyte elastase | [Definition]
ChEBI: A tripeptide derived from methoxysuccinyl-Ala-Ala-Pro-Val by conversion of the terminal carboxy group to the corresponding chloromethyl ketone. | [General Description]
N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone is a tetrapeptide, cell-permeable and non-cytotoxic inhibitor. | [Biochem/physiol Actions]
N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone acts as a competitive inhibitor of human leukocyte elastase (HLE). |
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| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
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