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65182-56-1

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65182-56-1 Structure

65182-56-1 Structure
IdentificationBack Directory
[Name]

3-AMINO-2-CHLORO-6-(TRIFLUOROMETHYL)PYRIDINE
[CAS]

65182-56-1
[Synonyms]

STAT1 Enhancer, 2-NP
8-Naphthyridin-2-yl)phenol
2-(1,8-Naphthyridin-2-ly)phenol
Phenol,2-(1,8-naphthyridin-2-yl)-
2-(1,8-Naphthyridin-2-yl)phenol 95+%
2-(2-Hydroxyphenyl)-1,8-naphthyridine
6-(1H-1,8-naphthyridin-2-ylidene)-1-cyclohexa-2,4-dienone
6-(1H-1,8-naphthyridin-2-ylidene)cyclohexa-2,4-dien-1-one
[Molecular Formula]

C14H10N2O
[MDL Number]

MFCD00203050
[MOL File]

65182-56-1.mol
[Molecular Weight]

222.24
Chemical PropertiesBack Directory
[Melting point ]

92-94°C
[storage temp. ]

room temp
[solubility ]

DMSO: ≥10mg/mL
[form ]

solid
[color ]

orange
Safety DataBack Directory
[Hazard Codes ]

Xn,T
[Risk Statements ]

22-41-36-25
[Safety Statements ]

26-39-45
[WGK Germany ]

3
[HS Code ]

2907199090
Hazard InformationBack Directory
[Uses]

2-(1,8-naphthyridin-2-yl)-Phenol is which selectively enhances STAT1 transcription activity.
[Biological Activity]

2-NP is a STAT1 Enhancer
[in vivo]

2-NP (0.5 mg/kg, subconjunctival injection, once daily for 3 days) alleviates corneal lesions and exhibits antiviral activity in Herpes simplex keratitis (HSK) mouse model[3].

Animal Model:Herpes simplex keratitis (HSK) model[3]
Dosage:0.5 mg/kg
Administration:subconjunctival injection, once daily for 3 days
Result:Alleviated corneal lesions in mice, reduced corneal opacity and neovascularization.
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

3-AMINO-2-CHLORO-6-(TRIFLUOROMETHYL)PYRIDINE(65182-56-1)1HNMR
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