| Identification | Back Directory | [Name]
Nsc293053 | [CAS]
65325-68-0 | [Synonyms]
Nsc293053
fluoromethylsulfinylbenzene
Benzene, [(fluoromethyl)sulfinyl]- | [Molecular Formula]
C7H7FOS | [MDL Number]
MFCD17013504 | [MOL File]
65325-68-0.mol | [Molecular Weight]
158.19 |
| Chemical Properties | Back Directory | [Melting point ]
0.3 °C | [Boiling point ]
283.1±15.0 °C(Predicted) | [density ]
1.29±0.1 g/cm3(Predicted) | [refractive index ]
1.5375 | [solubility ]
sol THF, CH2Cl2, CHCl3. |
| Hazard Information | Back Directory | [Uses]
Fluoromethyl Phenyl Sulfoxide is used for synthesis of fluoro ketones, fluoroalkenes, and aziridines. | [Preparation]
Fluoromethyl Phenyl Sulfoxide is prepared by the oxidation of Fluoromethyl Phenyl Sulfide with either N-Bromosuccinimide or
m-Chloroperbenzoic Acid (eq 1).[1c-f] Studies of the structure of fluoro(phenylsulfinyl)methyllithium,
investigated by NMR, suggest that lithium is bound to oxygen, rather than to the α-carbon atom.[2]
 | [storage]
Fluoromethyl Phenyl Sulfoxide uses in a fume hood. | [Purification Methods]
Pure compound of Fluoromethyl Phenyl Sulfoxide is obtained either by distillation or column chromatography on silica using
hexane-ethyl acetate (1:4). | [References]
1. (a) Schlosser, M. T 1978, 34, 3. (b) Rozen, S.; Filler, R. T 1985, 41, 1111. (c) More, K. M.; Wemple, J. S 1977, 791.
(d) McCarthy, J. R.; Peet, N. P.; LeTourneau, M. E.; Inbasekaran, M. JACS 1985, 107, 735. (e) Wnuk, S. F.; Robins, M.
J. JOC 1990, 55, 4757. (f) Robins, M. J.; Wnuk, S. F. JOC 1993, 58, 3800.
2. Nájera, C.; Yus, M.; H?ssig, R.; Seebach, D. HCA 1984, 67, 1100.
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