| Identification | Back Directory | [Name]
Cholan-24-amide, 3,7-dihydroxy-N-phenyl-, (3α,5β,7α)- (9CI) | [CAS]
65384-76-1 | [Synonyms]
Germination-IN-1
Cholan-24-amide, 3,7-dihydroxy-N-phenyl-, (3α,5β,7α)- (9CI) | [Molecular Formula]
C30H45NO3 | [MOL File]
65384-76-1.mol | [Molecular Weight]
467.69 |
| Hazard Information | Back Directory | [Uses]
Germination-IN-1 (compound 11) is a potent germination inhibitor with an IC50 of 4 μM. Germination-IN-2 shows anti-germination activity with 14% germination rate[1]. | [References]
[1] Sharma SK, et al. Studies on the Importance of the 7α-, and 12α- hydroxyl groups of N-Aryl-3α,7α,12α-trihydroxy-5β-cholan-24-amides on their Antigermination Activity Against a Hypervirulent Strain of Clostridioides (Clostridium) difficile. Bioorg Med Chem DOI:10.1016/j.bmc.2021.116503 |
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