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65494-95-3

65494-95-3 Structure

65494-95-3 Structure
IdentificationBack Directory
[Name]

Nsc97113
[CAS]

65494-95-3
[Synonyms]

Nsc97113
N6-Methyl-xylo-adenosine
9H-Purin-6-amine, N-methyl-9-β-D-xylofuranosyl-
[Molecular Formula]

C11H15N5O4
[MOL File]

65494-95-3.mol
[Molecular Weight]

281.27
Chemical PropertiesBack Directory
[Boiling point ]

649.1±65.0 °C(Predicted)
[density ]

1.85±0.1 g/cm3(Predicted)
[pka]

13.12±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

N6-Methyl-xylo-adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
[Definition]

ChEBI: Adenosine, N-methyl- is a purine nucleoside.
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
[2] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
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