| Identification | Back Directory | [Name]
Lineoyl LPA | [CAS]
65528-85-0 | [Synonyms]
Lineoyl LPA
18:2 Lyso PA
9,12-Octadecadienoic acid (9Z,12Z)-, (2R)-2-hydroxy-3-(phosphonooxy)propyl ester | [Molecular Formula]
C21H39O7P | [MOL File]
65528-85-0.mol | [Molecular Weight]
434.5 |
| Chemical Properties | Back Directory | [Boiling point ]
582.0±60.0 °C(Predicted) | [density ]
1.116±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
liquid | [pka]
1.82±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
1-Linoleoyl-sn-glycero-3-phosphate is used in the administration of a therapeutically effective amount of ENPP2 inhibitor PF-8380 to individuals in which increased levels of LPA subtype suggest an increased risk of cardiovascular disease due to chronic viral infection. | [Definition]
ChEBI: 1-linoleoyl-sn-glycerol 3-phosphate is a 1-acyl-sn-glycerol 3-phosphate having linoleyl (9Z,12Z-octadecadienoyl) as the 1-O-acyl group. It is a conjugate acid of a 1-linoleoyl-sn-glycero-3-phosphate(2-). | [Biological Activity]
18:2 Lysophosphatidic acid (LPA) is an active ingredient of gintoninwhich is a bioactive ligand of ginseng. LPA is synthesized in plants by the activity of the enzyme glycerol 3-phosphate acyltransferase (GPAT). LPA is an intermediate in the synthesis of phosphatidic acid (PA) and other phospholipids. Abnormal LPA metabolism is found in children with autism. |
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| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
| Company Name: |
Creative Enzymes
|
| Tel: |
1-516-855-7709 |
| Website: |
www.creative-enzymes.com |
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