ChemicalBook--->CAS DataBase List--->65829-22-3

65829-22-3

Request For Quotation
65829-22-3 Structure

65829-22-3 Structure
IdentificationBack Directory
[Name]

7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine, 7-[(2-fluorophenyl)methyl]-
[CAS]

65829-22-3
[Synonyms]

OYYF-175
7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine, 7-[(2-fluorophenyl)methyl]-
[Molecular Formula]

C17H14FN5
[MOL File]

65829-22-3.mol
[Molecular Weight]

307.33
Chemical PropertiesBack Directory
[Boiling point ]

643.6±65.0 °C(Predicted)
[density ]

1.47±0.1 g/cm3(Predicted)
[pka]

8.32±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

OYYF-175, an antimicrobial antifolate, is a dihydrofolate reductase (DHFR) inhibitor with an IC50 of 2.36 nM for Escherichia coli DHFR. OYYF-175 exhibits potent broad-spectrum antibacterial activities, especially against multi-drug resistant Gram-Negative-strains[1].
[References]

[1] Yue Li, et al. The discovery of 1, 3-diamino-7H-pyrrol[3, 2-f]quinazoline compounds as potent antimicrobial antifolates. Eur J Med Chem. 2022 Jan 15;228:113979. DOI:10.1016/j.ejmech.2021.113979
65829-22-3 suppliers list
Company Name: TargetMol Chemicals Inc.  
Telephone: 15002134094
Website: https://www.targetmol.cn/
Tags:65829-22-3 Related Product Information
25316-40-9 53123-88-9 555-60-2 20350-15-6 56-65-5 18883-66-4