| Identification | Back Directory | [Name]
4,5-DEHYDRO DHA | [CAS]
660429-97-0 | [Synonyms]
4,5-DEHYDRO DHA
OXENLKNOBTVOJA-JLNKQSITSA-N
4,5-DEHYDRO DOCOSAHEXAENOIC ACID
7Z,10Z,13Z,16Z,19Z-DOCOSAPENTAEN-4-YNOIC ACID
7,10,13,16,19-Docosapentaen-4-ynoic acid, (7Z,10Z,13Z,16Z,19Z)- | [Molecular Formula]
C22H30O2 | [MDL Number]
MFCD02259378 | [MOL File]
660429-97-0.mol | [Molecular Weight]
326.47 |
| Hazard Information | Back Directory | [Description]
Docosahexaenoic acid (DHA; 22:6ω3) is one of the essential dietary ω-3 unsaturated fatty acids and the preferred n-3 fatty acid for development of the brain and retina.1 4,5-dehydro DHA is a novel analog of DHA in which the double bond closest to the carboxyl group has been converted into an acetylene. 4,5-dehydro DHA is a novel compound that has not been studied in biological systems. However, the corresponding acetylene in the C-20 fatty acid series (5,6-dehydro arachidonic acid) is a well known inhibitor of 5-lipoxygenase.2 | [Uses]
(7Z,10Z,13Z,16Z,19Z)-Docosa-7,10,13,16,19-pentaen-4-ynoic acid is an ester product. | [Definition]
ChEBI: 4,5-dehydro Docosahexaenoic Acid is a very long-chain fatty acid. | [References]
1. Anderson, G.J., Connor, W.E., and Corliss, J.D. Docosahexaenoic acid is the preferred dietary n-3 fatty acid for the development of the brain and retina Pediatr. Res. 27,89-97(1990).
2. Sok, D.E., Han, C.Q., Pai, J.K., et al. Inhibition of leukotriene biosynthesis by acetylenic analogs Biochem. Biophys. Res. Commun. 107,101-108(1982). |
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