| Identification | Back Directory | [Name]
saframycin A | [CAS]
66082-27-7 | [Synonyms]
NSC 325663
saframycin A
N-[[(6S)-7α-Cyano-1,5,6,7,9,10,13,14,14aα,15-decahydro-2,11-dimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6α,15α-epimino-4H-isoquino[3,2-b][3]benzazocin-9β-yl]methyl]-2-oxopropionamide
Propanamide, N-[[(6S,7R,9R,14aS,15R)-7-cyano-1,5,6,7,9,10,13,14,14a,15-decahydro-2,11-dimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6,15-imino-4H-isoquino[3,2-b][3]benzazocin-9-yl]methyl]-2-oxo- | [Molecular Formula]
C29H30N4O8 | [MOL File]
66082-27-7.mol | [Molecular Weight]
562.57 |
| Hazard Information | Back Directory | [Uses]
Saframycin A has the effect of anti-Gram-positive bacteria. Saframycin A also has weak activity against Gram-negative bacteria and mycobacteria. Saframycin A has the effect of inhibiting mouse lymphocyte L-1210 with an ID50 of 0.0056 μM[1]. | [References]
[1] Ryo Tanifuji, et al. Chemo-enzymatic Total Syntheses of Jorunnamycin A, Saframycin A, and N-Fmoc Saframycin Y3. J Am Chem Soc. 2018 Aug 29;140(34):10705-10709. |
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