| Identification | Back Directory | [Name]
MANNOPENTAOSE-DI(N-ACETYL-D-*GLUCOSAMINE) | [CAS]
66091-47-2 | [Synonyms]
MAN-5 Glycan
(Man)5(GlcNAc)2
Oligomannose-5 glycan
OligoMannose-5(Man-5)
KWELUOKCUPRKJV-XUFDMPMHSA-N
Oligomannose-5 glycan (Man-5)
MANNOPENTAOSE-DI(N-ACETYL-D-*GLUCOSAMINE)
(Man)5(GlcNAc)2, Mannopentaose-di-(N-acetyl-D-glucosamine), Oligomannose-5 glycan
D-Glucose, O-α-D-mannopyranosyl-(1→3)-O-[α-D-mannopyranosyl-(1→6)]-O-α-D-mannopyranosyl-(1→6)-O-[α-D-mannopyranosyl-(1→3)]-O-β-D-mannopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→4)-2-(acetylamino)-2-deoxy-
O-alpha-D-Mannopyranosyl-(1-3)-O-[O-alpha-D-mannopyranosyl-(1-3)-O-[alpha-D-mannopyranosyl-(1-6)]-alpha-D-mannopyranosyl-(1-6)]-O-beta-D-mannopyranosyl-(1-4)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-2-(acetylamino)-2-deoxy-D-glucose | [Molecular Formula]
C46H78N2O36 | [MDL Number]
MFCD00467030 | [MOL File]
66091-47-2.mol | [Molecular Weight]
1235.11 |
| Chemical Properties | Back Directory | [Boiling point ]
1598.5±65.0 °C(Predicted) | [density ]
1.76±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [form ]
solid | [pka]
12.65±0.70(Predicted) | [InChIKey]
KIAGZJJOMMNKBW-UHFFFAOYSA-N | [SMILES]
CC(=O)NC(C=O)C(O)C(OC1OC(CO)C(OC2OC(COC3OC(COC4OC(CO)C(O)C(O)C4O)C(O)C(OC5OC(CO)C(O)C(O)C5O)C3O)C(O)C(OC6OC(CO)C(O)C(O)C6O)C2O)C(O)C1NC(C)=O)C(O)CO |
| Hazard Information | Back Directory | [Biochem/physiol Actions]
Antibodies bearing high levels of N-linked mannose-5 glycan (Man-5) have been found to exhibit enhanced antibody-dependent cell-mediated cytotoxicity (ADCC) when compared to antibodies with fucosylated complex or hybrid glycans. |
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| Company Name: |
Sigma-Aldrich
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| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
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