| Identification | Back Directory | [Name]
Phenol, 2-[(cyclohexylamino)methyl]-4-(1,1-dimethylethyl)-6-methyl- | [CAS]
6640-90-0 | [Synonyms]
NSC 48160
Phenol, 2-[(cyclohexylamino)methyl]-4-(1,1-dimethylethyl)-6-methyl- | [Molecular Formula]
C18H29NO | [MOL File]
6640-90-0.mol | [Molecular Weight]
275.43 |
| Hazard Information | Back Directory | [Uses]
NSC 48160 inhibits the growth of the pancreatic cancer cells with IC50s of 84.3 μM for CPFAC-1 and 94.5 μM for BxPC-3. NSC 48160 also induces pancreatic cancer cell apoptosis. NSC 48160 can improve metabolic syndromes, such as NASH, obesity and lipid metabolism disorders[1][2]. | [References]
[1] Li D, et al. A small-molecule induces apoptosis and suppresses metastasis in pancreatic cancer cells. Eur J Pharm Sci. 2013 Mar 12;48(4-5):658-67. DOI:10.1016/j.ejps.2012.12.023
[2] Liu zuijia, et al. Application of small molecule compound NSC48160 in preparation of medicine for treating non-alcoholic fatty liver disease. Patent. CN115869292 |
|
| Company Name: |
Bide Pharmatech Ltd.
|
| Telephone: |
400-1647117 13681763483 |
| Website: |
https://www.bidepharm.com/ |
|