| Identification | Back Directory | [Name]
AGARIC ACID | [CAS]
666-99-9 | [Synonyms]
agaric
AGARICIN
NSC 60429
NSC 65690
AGARIC ACID
laricicacid
AGARICIC ACID
AGARIC ACID(P)
Agaricinic acid
n-hexadecylcitricacid
alpha-cetylcitricacid
α-Hexadecylcitric acid
Agaric Acid n-Hydrate
3-nonadecanetricarboxylicacid,2-hydroxy-2
2-hydroxynonadecane-1,2,3-tricarboxylic acid
2-HYDROXY-1,2,3-NONADECANETRICARBOXYLIC ACID
2-Hydroxy-1,2,3-nonadecanetricarboxylic acid, Agaricic acid, Agaricin | [EINECS(EC#)]
211-566-5 | [Molecular Formula]
C22H40O7 | [MDL Number]
MFCD00002665 | [MOL File]
666-99-9.mol | [Molecular Weight]
416.55 |
| Chemical Properties | Back Directory | [Melting point ]
142° (dec) | [alpha ]
D19 -9° (NaOH) | [Boiling point ]
454.85°C (rough estimate) | [density ]
1.0867 (rough estimate) | [refractive index ]
1.5300 (estimate) | [storage temp. ]
-20°C Freezer, Under inert atmosphere | [solubility ]
Aqueous Base (Slightly), DMSO (Slightly) | [form ]
Solid | [pka]
2.93±0.36(Predicted) | [color ]
Pale Beige | [Merck ]
13,186 | [InChI]
1S/C22H40O7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18(20(25)26)22(29,21(27)28)17-19(23)24/h18,29H,2-17H2,1H3,(H,23,24)(H,25,26)(H,27,28) | [InChIKey]
HZLCGUXUOFWCCN-UHFFFAOYSA-N | [SMILES]
CCCCCCCCCCCCCCCCC(C(O)=O)C(O)(CC(O)=O)C(O)=O || CCCCCCCCCCCCCCCCC(C(O)=O)C(O)(CC(O)=O)C(O)=O |
| Hazard Information | Back Directory | [Uses]
antiperspirant | [Uses]
Has been used as antiperspirant. | [in vivo]
Agaric acid (1-4% of the diet; 3 weeks) inhibits lipogenesis in rats[3]. | Animal Model: | Female Sprague-Dawley rats weighing 170-185 g[3] | | Dosage: | 1% and 4% of the diet | | Administration: | 3 weeks | | Result: | Significantly affected weight gain and food intake.
Decreased fatty acid synthesis and increased unsaponifiable lipid formation in the liver.
Caused a significant decrease in fatty acid synthesis and unsaponifiable lipid synthesis in adipose tissue at a dose of 4%.
|
| [Purification Methods]
Crystallise the acid from EtOH. The trihydrazide has m 170o(dec) (from EtOH). [Brand.nge et al. Acta Chem Scand B 31 307 1977, Beilstein 3 I 186, 3 II 372, 3 III 1109, 3 IV 1284.] |
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| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
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