ChemicalBook--->CAS DataBase List--->66635-92-5

66635-92-5

66635-92-5 Structure

66635-92-5 Structure
IdentificationBack Directory
[Name]

(S)-Ketorolac
[CAS]

66635-92-5
[Synonyms]

Ketorolac S-IsoMer
(S)-Ketorolac ISO 9001:2015 REACH
Ketorolac impurity 2/Ketorolac S-Isomer
1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro-, (1S)-
[Molecular Formula]

C15H13NO3
[MOL File]

66635-92-5.mol
[Molecular Weight]

255.27
Chemical PropertiesBack Directory
[Melting point ]

160-167?C
[storage temp. ]

Refrigerator
Safety DataBack Directory
[Symbol(GHS) ]


GHS06
[Signal word ]

Danger
[Hazard statements ]

H301
[Precautionary statements ]

P264-P270-P301+P310-P405-P501
Hazard InformationBack Directory
[Chemical Properties]

Off-White Solid
[Uses]

(S)-Ketorolac is the S-enantiomer of Ketorolac. The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.
[Uses]

The R-enantiomer of Ketorolac. The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.
[Definition]

ChEBI: A 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid that has S configuration. While (S)-ketorolac is a COX1 and COX2 inhibitor, both enantiomers exhibit analgesic effects. Racemic ketorolac, known s mply as ketorolac, is used (mainly as the tromethamine salt) as a potent analgesic for the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis.
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