| Identification | Back Directory | [Name]
L-Valine, 3-methyl-N-(trifluoroacetyl)- (9CI) | [CAS]
666832-71-9 | [Synonyms]
Trifluoroacetyl L-Tert-Leucine
N-Trifluoroacetyl L-Tert-Leucine
3-methyl-n - (trifluoroacetyl) - L-valine
L-Valine, 3-methyl-N-(trifluoroacetyl)- (9CI)
(S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoic acid | [EINECS(EC#)]
674-976-7 | [Molecular Formula]
C8H12F3NO3 | [MDL Number]
MFCD12795957 | [MOL File]
666832-71-9.mol | [Molecular Weight]
227.18 |
| Chemical Properties | Back Directory | [Boiling point ]
308.1±42.0 °C(Predicted) | [density ]
1.276±0.06 g/cm3(Predicted) | [storage temp. ]
Store at room temperature | [pka]
3.08±0.10(Predicted) | [Appearance]
White to off-white Solid | [InChI]
InChI=1S/C8H12F3NO3/c1-7(2,3)4(5(13)14)12-6(15)8(9,10)11/h4H,1-3H3,(H,12,15)(H,13,14)/t4-/m1/s1 | [InChIKey]
FCTPLAZWXGEGKO-SCSAIBSYSA-N | [SMILES]
C(O)(=O)[C@H](C(C)(C)C)NC(C(F)(F)F)=O |
| Hazard Information | Back Directory | [Uses]
L-Valine, 3-methyl-N-(trifluoroacetyl)- (9CI) is a pharmaceutical intermediate composition for the preparation of nitrile-containing antiviral compounds. | [Application]
L-Valine, 3-methyl-N-(trifluoroacetyl)- (9CI) is a key pharmaceutical intermediate for the anti-COVID-19 drug nirmatrelvir (trade name Paxlovid). Nirmatrelvir is an oral SARS-CoV-2 main protease (Mpro) inhibitor that, when used in combination with ritonavir (i.e., Paxlovid), can effectively inhibit the replication of the SARS-CoV-2 virus and is used to treat patients with mild to moderate COVID-19. |
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| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
AF Biochem Co., Ltd.
|
| Telephone: |
+86-028-60911900 13540204019 |
| Website: |
www.afbiochem.com |
|