| Identification | Back Directory | [Name]
[[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate | [CAS]
6674-45-9 | [Synonyms]
Diguanosine 5′-triphosphate
GP3G (Unmethylated Cap Analog)
Guanosine-5'-triphosphate-5'-Guanosine
GP3G (Unmethylated Cap Analog) - solution
[[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate | [Molecular Formula]
C20H27N10O18P3 | [MDL Number]
MFCD34474133 | [MOL File]
6674-45-9.mol | [Molecular Weight]
788.41 |
| Hazard Information | Back Directory | [Uses]
Diguanosine 5′-triphosphate (Gp3G) is a dinucleoside triphosphates. Diguanosine 5′-triphosphate also is a virus-specific oligonucleotide. Diguanosine 5′-triphosphate is needed for the synthesis of RNA during the transcription process[1][2]. | [References]
[1] M Yamakawa, et al. Priming of reovirus transcription by GppppG and formation of CpG(5')GpC. Proc Natl Acad Sci U S A. 1982 Oct;79(20):6142-6. DOI:10.1073/pnas.79.20.6142
[2] Emmanuel Klein, et al. Synthesis of enzymatically and chemically non-hydrolyzable analogues of dinucleoside triphosphates Ap(3)A and Gp(3)G. J Org Chem. 2002 Jan 11;67(1):146-53. DOI:10.1021/jo015836e |
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