| Identification | Back Directory | [Name]
Cianopramine | [CAS]
66834-24-0 | [Synonyms]
Ro-11-2465
Cianopramine
Cyanimipramine
Cyanoimipramine
3-Cyanoimipramine
5-[3-(Dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine-3-carbonitrile
5H-Dibenz[b,f]azepine-3-carbonitrile, 5-[3-(dimethylamino)propyl]-10,11-dihydro- | [Molecular Formula]
C20H23N3 | [MDL Number]
MFCD00868049 | [MOL File]
66834-24-0.mol | [Molecular Weight]
305.42 |
| Hazard Information | Back Directory | [Uses]
Cianopramine (Cyanimipramine) is a tricyclic antidepressant, and a potent inhibitor of neuronal serotonin (5-HT) uptake. Cianopramine blocks central and peripheral 5-HT receptors[1][2]. | [References]
[1] Eichler HG, et al. Effect of cianopramine, a tricyclic antidepressant, on platelet serotonin uptake and peripheral adrenergic function. Clin Pharmacol Ther. 1984 Oct;36(4):542-5. DOI:10.1038/clpt.1984.216
[2] Pawlowski L, et al. Ro 11-2465 (cyan-imipramine), citalopram and their N-desmethyl metabolites: effects on the uptake of 5-hydroxytryptamine and noradrenaline in vivo and related pharmacological activities. Psychopharmacology (Berl). 1985;86(1-2):156-63. DOI:10.1007/BF00431702 |
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