ChemicalBook--->CAS DataBase List--->66845-32-7

66845-32-7

66845-32-7 Structure

66845-32-7 Structure
IdentificationBack Directory
[Name]

Nsc290127
[CAS]

66845-32-7
[Synonyms]

Nsc290127
Oxaliplatin Impurity F
Oxaliplatin Related CoMpound F
Oxaliplatin Related Compound F (25 mg)
Diiodo(trans-l-1,2-cyclohexanediamine)platinum
(trans-R,R-1,2-Diaminocyclohexane)diiodoplatinum
(trans-1R,2R-1,2-Diaminocyclohexane)diiodoplatinum
[SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-κN,κN') Diiodoplatinum
Oxaliplatin Related Compound F ([SP-4-2-(1R-trans)]-(1,2-cyclohexanediamine-N,N'') diiodidoplatinum( (1481260)
Oxaliplatin Related Compound F (25 mg) ([SP-4-2-(1R-trans)]-(1,2-cyclohexanediamine-N,N') diiodidoplatinum(II))
[Molecular Formula]

C6H14I2N2Pt
[MOL File]

66845-32-7.mol
[Molecular Weight]

563.076
Chemical PropertiesBack Directory
[Melting point ]

>300°C
[storage temp. ]

-20°C Freezer
[solubility ]

DMSO (Slightly)
[form ]

Solid
[color ]

Light Yellow
[Major Application]

pharmaceutical (small molecule)
[InChI]

1S/C6H12N2.2HI.Pt/c7-5-3-1-2-4-6(5)8;;;/h5-8H,1-4H2;2*1H;/q-2;;;+4/p-2
[InChIKey]

KEZVWGKGXZSYRH-UHFFFAOYSA-L
[SMILES]

[Pt+2](I)I.[N-H]C1C(CCCC1)[N-H]
Safety DataBack Directory
[Symbol(GHS) ]

Health Hazard (GHS08)Corrosion (GHS05)Skull and Crossbones (GHS06)
GHS08,GHS05,GHS06
[Signal word ]

Danger
[Hazard statements ]

H360-H301-H335-H290-H350-H340-H331-H315-H311-H319
[Precautionary statements ]

P264-P270-P301+P310-P321-P330-P405-P501-P234-P390-P404-P261-P271-P304+P340-P311-P321-P403+P233-P405-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P280-P302+P352-P312-P322-P361-P363-P405-P501
[WGK Germany ]

WGK 3
[HS Code ]

2843900000
[Storage Class]

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
[Hazard Classifications]

Carc. 2
Eye Dam. 1
Lact.
Muta. 2
Repr. 1B
Resp. Sens. 1B
Skin Sens. 1
STOT RE 1
Hazard InformationBack Directory
[Uses]

[SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-κN,κN'')diiodoplatinum is a potential antitumor agent. Impurity of Oxiplatin (O845075), third generation platinum complex. An antitumor agent with activity against colorectal cancer. Cytotoxicity follows the formation of adducts with DNA. Antineoplastic.
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