| Identification | Back Directory | [Name]
BETA-CHLORNALTREXAMINE 2HCL | [CAS]
67025-98-3 | [Synonyms]
BETA-CHLORNALTREXAMINE 2HCL
chlornaltrexaminedihydrochloride
dihydrochloride,(5-alpha,6-beta)-xy
B-CHLORNALTREXAMINE DIHYDROCHLORIDE (B-C NA) OPOID ANTA | [Molecular Formula]
C24H32Cl2N2O3.2ClH | [MDL Number]
MFCD00069321 | [MOL File]
67025-98-3.mol | [Molecular Weight]
540.356 |
| Hazard Information | Back Directory | [Uses]
β-Chlornaltrexamine dihydrochloride (β-CNA dihydrochloride) is a potent long-term opioid receptor blocker. β-Chlornaltrexamine dihydrochloride can effectively block the inhibitory effect of κ opioid receptor agonists on dopamine release. β-Chlornaltrexamine dihydrochloride can be used to study the mechanism of pain perception[1]. | [References]
[1] Reichard K L, et al. Regulation of kappa opioid receptor inactivation depends on sex and cellular site of antagonist action[J]. Molecular Pharmacology, 2020, 98(5): 548-558. DOI:10.1124/molpharm.120.000124 |
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