ChemicalBook--->CAS DataBase List--->67247-11-4

67247-11-4

67247-11-4 Structure

67247-11-4 Structure
IdentificationBack Directory
[Name]

FOR-MET-LEU-PHE-LYS-OH
[CAS]

67247-11-4
[Synonyms]

fMLFK
FOR-MET-LEU-PHE-LYS
FOR-MET-LEU-PHE-LYS-OH
N-FORMYL-MET-LEU-PHE-LYS
L-Lysine, N-formyl-L-methionyl-L-leucyl-L-phenylalanyl-
[Molecular Formula]

C27H43N5O6S
[MDL Number]

MFCD00079844
[MOL File]

67247-11-4.mol
[Molecular Weight]

565.73
Chemical PropertiesBack Directory
[Boiling point ]

947.3±65.0 °C(Predicted)
[density ]

1.193±0.06 g/cm3(Predicted)
[storage temp. ]

-15°C
[form ]

Solid
[pka]

3.30±0.10(Predicted)
[color ]

White to off-white
[Sequence]

Formyl-Met-Leu-Phe-Lys
Hazard InformationBack Directory
[Uses]

N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D2817.32G, respectively[1].
[References]

[1] He HQ, et al. Structural determinants for the interaction of formyl peptide receptor 2 with peptide ligands. J Biol Chem. 2014 Jan 24;289(4):2295-306. DOI:10.1074/jbc.M113.509216
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