| Identification | Back Directory | [Name]
FOR-MET-LEU-PHE-LYS-OH | [CAS]
67247-11-4 | [Synonyms]
fMLFK
FOR-MET-LEU-PHE-LYS
FOR-MET-LEU-PHE-LYS-OH
N-FORMYL-MET-LEU-PHE-LYS
L-Lysine, N-formyl-L-methionyl-L-leucyl-L-phenylalanyl- | [Molecular Formula]
C27H43N5O6S | [MDL Number]
MFCD00079844 | [MOL File]
67247-11-4.mol | [Molecular Weight]
565.73 |
| Chemical Properties | Back Directory | [Boiling point ]
947.3±65.0 °C(Predicted) | [density ]
1.193±0.06 g/cm3(Predicted) | [storage temp. ]
-15°C | [form ]
Solid | [pka]
3.30±0.10(Predicted) | [color ]
White to off-white | [Sequence]
Formyl-Met-Leu-Phe-Lys |
| Hazard Information | Back Directory | [Uses]
N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D2817.32G, respectively[1]. | [References]
[1] He HQ, et al. Structural determinants for the interaction of formyl peptide receptor 2 with peptide ligands. J Biol Chem. 2014 Jan 24;289(4):2295-306. DOI:10.1074/jbc.M113.509216 |
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