| Identification | Back Directory | [Name]
Kansuinine E | [CAS]
672945-84-5 | [Synonyms]
Kansuinine E
3-Pyridinecarboxylic acid, (1aR,3S,4S,5S,7R,7aR,8S,9S,10aR,12R,12aS)-5,7,8,10a-tetrakis(acetyloxy)-4-(benzoyloxy)tetradecahydro-2,2,9,12-tetramethyl-6-methylene-11-oxo-2H-cyclopenta[5,6]cyclododec[1,2-b]oxiren-3-yl ester | [Molecular Formula]
C41H47NO14 | [MDL Number]
MFCD34471626 | [MOL File]
672945-84-5.mol | [Molecular Weight]
777.81 |
| Hazard Information | Back Directory | [Uses]
Kansuinine E is a plant-derived nitric oxide inhibitor (IC50=6.3 μM). Kansuinine E belongs to jatrophane-type diterpenoids and is isolated from the roots of E. kansui[1]. | [References]
[1] Lee JW, et al. Jatrophane and ingenane-type diterpenoids from Euphorbia kansui inhibit the LPS-induced NO production in RAW 264.7 cells. Bioorg Med Chem Lett. 2016;26(14):3351-3354. DOI:10.1016/j.bmcl.2016.05.035 |
|
|