| Identification | Back Directory | [Name]
1,3-DIPALMITOYL-GLYCERO-2-PHOSPHOETHANOLAMINE | [CAS]
67303-93-9 | [Synonyms]
1,3-DPPE
1,3-Dipalmitoyl glycero-2-PE
1,3-Dipalmitoyl-sn-glycero-2-PE
1,3-Dipalmitoyl-rac-glycero-2-PE
1,3-dipalmitoylphosphatidylethanolamine
1,3-DIPALMITOYL-GLYCERO-2-PHOSPHOETHANOLAMINE
1,3-Dipalmitoyl-sn-glycero-2-phosphoethanolamine
2-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,3-diyl dipalmitate
2-[2-aminoethoxy(hydroxy)phosphoryl]oxy-3-hexadecanoyloxypropyl] hexadecanoate
Hexadecanoic acid, 1,1'-[2-[[(2-aminoethoxy)hydroxyphosphinyl]oxy]-1,3-propanediyl] ester | [Molecular Formula]
C37H74NO8P | [MDL Number]
MFCD00038196 | [MOL File]
67303-93-9.mol | [Molecular Weight]
691.96 |
| Chemical Properties | Back Directory | [Melting point ]
192-193 °C (decomp) | [Boiling point ]
723.4±70.0 °C(Predicted) | [density ]
1.010±0.06 g/cm3(Predicted) | [storage temp. ]
Store at 0°C | [solubility ]
Chloroform: 3 mg/ml | [form ]
A crystalline solid | [pka]
1.11±0.50(Predicted) |
| Hazard Information | Back Directory | [Uses]
1,3-Dipalmitoyl-glycero-2-phosphoethanolamine is a phospholipid containing the saturated long-chain (16:0) stearic acid inserted at the sn-1 and sn-3 positions and PE at the sn-2 site. It can be used in the generation of micelles, liposomes, and other types of artificial membranes. | [References]
[1] Sim?es S, Moreira JN, Fonseca C, Düzgüne? N, de Lima MC. On the formulation of pH-sensitive liposomes with long circulation times.?Adv Drug Deliv Rev. 2004;56(7):947-965. DOI:10.1016/j.addr.2003.10.038
[2] Fattal E, Couvreur P, Dubernet C. "Smart" delivery of antisense oligonucleotides by anionic pH-sensitive liposomes.?Adv Drug Deliv Rev. 2004;56(7):931-946. DOI:10.1016/j.addr.2003.10.037 |
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