| Identification | Back Directory | [Name]
(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase | [CAS]
67338-98-1 | [Synonyms]
(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase |
| Hazard Information | Back Directory | [Uses]
beta-1,4-N-Acetylgalactosaminyltransferase (CgtA) (GM2/GD2 synthase) is a key enzyme which catalyzes the conversion of GM3, GD3 and lactosylceramide (LacCer) to GM2, GD2 and asialo-GM2 (GA2), respectively. beta-1,4-N-Acetylgalactosaminyltransferase (CgtA) is a key enzyme to control the synthesis of brain-enriched complex gangliosides[1]. | [References]
[1] Furukawa K, et al. Beta1,4-N-acetylgalactosaminyltransferase--GM2/GD2 synthase: a key enzyme to control the synthesis of brain-enriched complex gangliosides. Biochim Biophys Acta. 2002 Dec 19;1573(3):356-62. DOI:10.1016/s0304-4165(02)00403-8 |
|
|