| Identification | Back Directory | [Name]
1,4-Butanediamine, N4-[[4-[[(1H-imidazol-2-ylmethyl)[(1-methyl-1H-imidazol-2-yl)methyl]amino]methyl]phenyl]methyl]-N1,N1-dipropyl- | [CAS]
675135-69-0 | [Synonyms]
CXCR4 antagonist 1
1,4-Butanediamine, N4-[[4-[[(1H-imidazol-2-ylmethyl)[(1-methyl-1H-imidazol-2-yl)methyl]amino]methyl]phenyl]methyl]-N1,N1-dipropyl- | [Molecular Formula]
C27H43N7 | [MOL File]
675135-69-0.mol | [Molecular Weight]
465.68 |
| Hazard Information | Back Directory | [Uses]
CXCR4 antagonist 1 is a potent CXCR4 antagonist. CXCR4 antagonist 1 has anti-HIV activity[1]. | [IC 50]
HIV-1; CXCR4 | [References]
[1] Yuta Hikichi, et al. Increased HIV-1 Sensitivity to Neutralizing Antibodies by Mutations in the Env V3-coding Region for Resistance to CXCR4 Antagonists. J Gen Virol. 2016 Sep;97(9):2427-2440. DOI:10.1099/jgv.0.000536 |
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