| Identification | Back Directory | [Name]
MALEIC ANHYDRIDE (1,4-13C2) | [CAS]
67519-25-9 | [Synonyms]
MALEIC ANHYDRIDE (1,4-13C2)
SUCCINIC ANHYDRIDE (1,4-13C2, 99%) | [Molecular Formula]
C4H2O3 | [MDL Number]
MFCD01075501 | [MOL File]
67519-25-9.mol | [Molecular Weight]
100.07 |
| Hazard Information | Back Directory | [Uses]
Succinic anhydride-13C2 is the 13C labeled Succinic anhydride[1]. Succinic anhydride is a cyclic anhydride and a nonclaevable ADC linker extracted from patent WO2009064913A1. Succinic anhydride can react with compound 4 of the patent to link the proagent to an amine or hydroxy 1 group of a targeting polypeptide[2]. | [References]
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Dale Boger.et al. Chimer containing a targeting portion linked to a scission-activated duocarmycin-type prodrug. WO2009064913A1. |
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