| Identification | Back Directory | [Name]
prolylglutamic acid | [CAS]
67644-00-2 | [Synonyms]
Pro-Glu
Pro-Glu-OH
L-Pro-L-Glu-OH
prolylglutamic acid
L-Glutamic acid, L-prolyl-
(2S)-2-{[(2S)-pyrrolidin-2-yl]formamido}pentanedioic acid | [Molecular Formula]
C10H16N2O5 | [MDL Number]
MFCD00037872 | [MOL File]
67644-00-2.mol | [Molecular Weight]
244.24 |
| Hazard Information | Back Directory | [Uses]
H-Pro-Glu-OH is a protein secreted by pathogenic mycobacteria through the Type VII secretion system. H-Pro-Glu-OH targets LipY lipases to the cell Surface via the ESX-5 Pathway[1]. | [Definition]
ChEBI: A dipeptide formed from L-proline and L-glutamic acid residues. | [References]
[1] Daleke MH, et al. Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) protein domains target LipY lipases of pathogenic mycobacteria to the cell surface via the ESX-5 pathway. J Biol Chem. 2011 May 27;286(21):19024-34. DOI:10.1074/jbc.M110.204966 |
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