| Identification | Back Directory | [Name]
5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide | [CAS]
676500-67-7 | [Synonyms]
CB-5945
ADL-5945
Bevenopran
Inhibitor,CB 5945,Bevenopran,CB5945,inhibit,Opioid Receptor,ADL 5945,ADL5945
5-[2-methoxy-4-[[2-(oxan-4-yl)ethylamino]methyl]phenoxy]pyrazine-2-carboxamide
5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
2-PYRAZINECARBOXAMIDE, 5-[2-METHOXY-4-[[[2-(TETRAHYDRO-2H-PYRAN-4-YL)ETHYL]AMINO]METHYL]PHENOXY]- | [Molecular Formula]
C20H26N4O4 | [MDL Number]
MFCD26967979 | [MOL File]
676500-67-7.mol | [Molecular Weight]
386.44 |
| Chemical Properties | Back Directory | [Melting point ]
133 - 136 °C | [Boiling point ]
575.0±50.0 °C(Predicted) | [density ]
1.204±0.06 g/cm3(Predicted) | [storage temp. ]
Refrigerator, under inert atmosphere | [solubility ]
Acetonitrile (Slightly), Chloroform (Slightly) | [form ]
Solid | [pka]
14.06±0.50(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
Bevenopran, is a peripheral μ-opioid receptor antagonist. | [Definition]
ChEBI:Bevenopran is an aromatic ether. | [in vivo]
Bevenopran is a peripheral μ-opioid receptor antagonist. Bevenopran is currently under investigation for the treatment of opioid-induced bowel dysfunction (OBD)[1]. Bevenopran tends to increase bowel movement (BM) frequency, especially for 0.1 mg twice daily and 4 mg daily, respectively[1]. | [IC 50]
μ Opioid Receptor/MOR | [storage]
Store at -20°C |
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cjbscvictory
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Bide Pharmatech Ltd.
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