| Identification | Back Directory | [Name]
N,N-DIMETHYLPHOSPHORAMIDODICHLORIDATE | [CAS]
677-43-0 | [Synonyms]
DMPADC
NSC 203138
(CH3)2NPOCl2
Dimethylamidophosphoric Dichlor
Dichlorophosphoric dimethylamide
dimethyl-phosphoramidicdichlorid
dimethylphosphoramidicdichloride
Dimethylphosphoramidic dichloride
dichlorophosphoryl(dimethyl)amine
DIMETHYLAMINOPHOSPHORYL DICHLORIDE
DIMETHYLAMIDOPHOSPHORIC DICHLORIDE
N,N-Dimethyl-phosphoramid-dichlorid
DIMETHYLAMINE PHOSPHORYL DICHLORIDE
N,N-DIMETHYLPHOSPHORAMIC DICHLORIDE
(Dimethylamino)phosphonic dichloride
N,N-dimethyl-phosphoramidedichloride
Phosphoramidic dichloride, dimethyl-
N,N-dimethylamino-phosphorylchloride
(Dimethylamino)dichlorophosphineoxide
N,N-DIMETHYLPHOSPHORAMIDIC DICHLORIDE
N,N-DIMETHYLPHOSPHORAMIDODICHLORIDATE
Dichloro(dimethylamino)phosphine oxide
N,N-Dimethylaminophosphoryl dichloride
Dimethylamidophosphoric acid dichloride
Phosphoramidic dichloride, N,N-dimethyl-
N,N-Dimethylphosporamidic aciddichloride
N-dichlorophosphoryl-N-methylmethanamine
PHOSPHORIC ACID DIMETHYLAMIDE DICHLORIDE
N-dichlorophosphoryl-N-methyl-methanamine
Dimethylamidophosphoric dichloride, DMPADC
N,N-Dimethylphosphoramic dichloride≥ 98%(GC)
677-43-0 N,N-DIMETHYLPHOSPHORAMIDODICHLORIDATE
N,N-Dimethylphosphoramic dichloride >=98.0% (AT)
Dimethylaminophosphoryl dichloride~N,N-Dimethylphosphoramic dichloride~DMPADC
N,N-Dimethylphosphoramidic Dichloride
Phosphoric Acid Dimethylamide Dichloride | [EINECS(EC#)]
211-641-2 | [Molecular Formula]
C2H6Cl2NOP | [MDL Number]
MFCD00013896 | [MOL File]
677-43-0.mol | [Molecular Weight]
161.95 |
| Chemical Properties | Back Directory | [Boiling point ]
77-79 °C11 mm Hg(lit.)
| [density ]
1.362 g/mL at 20 °C(lit.)
| [refractive index ]
n20/D 1.464
| [Fp ]
89-90°C/20mm | [storage temp. ]
2-8°C
| [solubility ]
Miscible with dimethoxyethane. | [form ]
Oil to Semi-Solid | [pka]
-6.60±0.70(Predicted) | [color ]
Colourless to Off-White | [Sensitive ]
Moisture Sensitive | [BRN ]
969956 | [Stability:]
Hygroscopic, Moisture Sensitive | [InChI]
InChI=1S/C2H6Cl2NOP/c1-5(2)7(3,4)6/h1-2H3 | [InChIKey]
YNHXBEVSSILHPI-UHFFFAOYSA-N | [SMILES]
P(N(C)C)(Cl)(Cl)=O | [CAS DataBase Reference]
677-43-0 | [EPA Substance Registry System]
N,N-Dimethyl phosphoramidic dichloride (677-43-0) |
| Hazard Information | Back Directory | [Chemical Properties]
Light yellow liquid | [Application]
N,N-dimethylphosphoramidodichloridate is an electrophilic phosphorylating reagent used to convert vicinal diols to alkenes and to activate carboxylic acids and alcohols towards nucleophiles. | [Uses]
N,N-Dimethylphosphoramidodichloridate is used in the synthesis of phosphoramidates as well as (RS)-ethyl N,N-dimethylphosphoramidocyanidate (Nerve agent GA) which is used as a chemical weapon. It forms active intermediates, which react with alcohols in situ to give esters. It is also used to convert primary alcohols to alkyl chlorides. Furthe, it serves as an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff. In addition to this, it reacts with 1,2 diols to prepare cyclic phosphoric amides followed by alkenes after reduction. | [Preparation]
N,N-DIMETHYLPHOSPHORAMIDODICHLORIDATE is obtained by treatment of Phosphorus Oxychloride with dimethylamine. |
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