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67731-19-5

67731-19-5 Structure

67731-19-5 Structure
IdentificationBack Directory
[Name]

N-[5-Hydroxy-5-(hydroxymethyl)-3-imino-2-methoxy-1-cyclohexen-1-yl]glycine
[CAS]

67731-19-5
[Synonyms]

Palythine
(5-hydroxy-5-(hydroxymethyl)-3-imino-2-methoxycyclohex-1-en-1-yl)glycine
N-[5-Hydroxy-5-(hydroxymethyl)-3-imino-2-methoxy-1-cyclohexen-1-yl]glycine
Glycine, N-[(5S)-5-hydroxy-5-(hydroxymethyl)-3-imino-2-methoxy-1-cyclohexen-1-yl]-
[Molecular Formula]

C10H16N2O5
[MOL File]

67731-19-5.mol
[Molecular Weight]

244.24
Chemical PropertiesBack Directory
[Boiling point ]

530.3±50.0 °C(Predicted)
[density ]

1.46±0.1 g/cm3(Predicted)
[pka]

4.14±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

Palythine is a photoprotective and antioxidant agent. Palythine exhibits photoprotective and antioxidant activities by absorbing ultraviolet radiation (UVR) energy and dissipating it as heat, as well as through antioxidant mechanisms such as direct chemical quenching and Nrf2 pathway activation, reducing cell death, DNA damage, inflammation, and oxidative stress. Palythine is promising for research of skin-related diseases such as skin cancer, photoaging, and photosensitivity disorders[1].
[Definition]

ChEBI: Palythine is an organonitrogen compound and an organooxygen compound. It is functionally related to an alpha-amino acid.
[References]

[1] Lawrence KP, et al. Molecular photoprotection of human keratinocytes in vitro by the naturally occurring mycosporine-like amino acid palythine. Br J Dermatol. 2018 Jun;178(6):1353-1363. DOI:10.1111/bjd.16125
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