ChemicalBook--->CAS DataBase List--->68077-27-0

68077-27-0

68077-27-0 Structure

68077-27-0 Structure
IdentificationBack Directory
[Name]

Norfloxacinehydrochloride
[CAS]

68077-27-0
[Synonyms]

NorfloxacineHCl
Norfloxacinehydrochloride
Hydrochloric acid and norfloxacin
Norfloxacinehydrochloride USP/EP/BP
[Molecular Formula]

C16H19ClFN3O3
[MOL File]

68077-27-0.mol
[Molecular Weight]

355.792
Chemical PropertiesBack Directory
[Melting point ]

>300 °C
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Powder
Safety DataBack Directory
[Hazard Codes ]

F,C
[Risk Statements ]

11-34
[Safety Statements ]

16-26-36/37/39-45
Hazard InformationBack Directory
[Uses]

Norfloxacin hydrochloride (MK-0366 hydrochloride) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase.
[storage]

Store at -20°C
[References]

[1] Nelson JM, et al. Fluoroquinolone-resistant Campylobacter species and the withdrawal of fluoroquinolones from use in poultry: a public health success story. Clin Infect Dis. 2007 Apr 1;44(7):977-80. Epub 2007 Feb 14. DOI:10.1086/512369
[2] Padeiskaia EN. Norfloxacin: more than 20 years of clinical use, the results and place among fluoroquinolones in modern chemotherapy for infections. Antibiot Khimioter. 2003;48(9):28-36. PMID:15002177
[3] Rafalsky V, et al. Quinolones for uncomplicated acute cystitis in women. Cochrane Database Syst Rev. 2006 Jul 19;(3):CD003597. DOI:10.1002/14651858.CD003597.pub2
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