Chemical Properties | Back Directory | [Boiling point ]
594.6±60.0 °C(Predicted) | [density ]
1.336±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [pka]
17.17±0.30(Predicted) |
Hazard Information | Back Directory | [Uses]
AP-C2 is a potent guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2[1]. | [References]
[1] Marcel J C Bijvelds, et al. Selective inhibition of intestinal guanosine 3',5'-cyclic monophosphate signaling by small-molecule protein kinase inhibitors. J Biol Chem. 2018 May 25;293(21):8173-8181. DOI:10.1074/jbc.RA118.002835 |
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