| Identification | Back Directory | [Name]
N-(4-chlorophenyl)-2-[4-(4-chlorophenyl)-1-oxophthalazin-2(1H)-yl]acetamide | [CAS]
684234-56-8 | [Synonyms]
WAY-323092
PARP-1-IN-4
2(1H)-Phthalazineacetamide, N,4-bis(4-chlorophenyl)-1-oxo-
N-(4-chlorophenyl)-2-[4-(4-chlorophenyl)-1-oxophthalazin-2(1H)-yl]acetamide | [Molecular Formula]
C22H15Cl2N3O2 | [MOL File]
684234-56-8.mol | [Molecular Weight]
424.28 |
| Hazard Information | Back Directory | [Uses]
PARP-1-IN-4 is a PARP-1 inhibitor. PARP-1-IN-4 has inhibitory activity against PARP-1 with IC50 value of 302 μM. PARP-1-IN-4 can be used for the research of lung adenocarcinoma[1]. | [References]
[1] Almahli H, et al. Development of novel synthesized phthalazinone-based PARP-1 inhibitors with apoptosis inducing mechanism in lung cancer. Bioorg Chem. 2018;77:443-456. DOI:10.1016/j.bioorg.2018.01.034 |
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