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Mollicellin H is a secondary metabolite of the fungus C. brasiliense and has a wide range of biological activities, including immunomodulation, cytotoxicity and anti-tumor effects. The growth inhibitory effects (GI50s) of Mollicellin H on human breast cancer (Bre04), human lung (Lu04) and human neuroma (N04) cell lines are 5.1 μg/mL, 6.5 μg/mL and 2.5 μg/mL respectively[1]. | [Definition]
ChEBI: A member of the class of depsidones that is 11H-dibenzo[b,e][1,4]dioxepine substituted by hydroxy groups at position 3 and 7, methyl group at positions 1 and 9, a prenyl group at position 8, an oxo group at position 11 and
formyl group at position 4. Isolated from Chaetomium brasiliense it exhibits cytotoxic activity. | [References]
[1] Li G Y, et al. Secondary metabolites from the fungus Chaetomium brasiliense[J]. Helvetica Chimica Acta, 2008, 91(1): 124-129. |
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