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6879-02-3

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6879-02-3 Structure

6879-02-3 Structure
IdentificationBack Directory
[Name]

Tylocrebrine
[CAS]

6879-02-3
[Synonyms]

Nsc-60387
Tylocrebine
Tylocrebrin
Brn 1555044
Tylocrebrine
Lylocrebrine
Tylocrebrinel
Tylocerebrine
Dibenzo(F,H)pyrrolo(1,2-B)isoquinoline, 9,11,12,13,13A,14-hexahydro-2,3,5,6-tetramethoxy-
[13aR,(+)]-9,11,12,13,13a,14-Hexahydro-2,3,5,6-tetramethoxydibenzo[f,h]pyrrolo[1,2-b]isoquinoline
Dibenzo[f,h]pyrrolo[1,2-b]isoquinoline, 9,11,12,13,13a,14-hexahydro-2,3,5,6-tetramethoxy-, (13aR)-
Dibenzo(F,H)pyrrolo(1,2-B)isoquinoline, 9,11,12,13,13A,14-hexahydro-2,3,5,6-tetramethoxy-, (R)- (9ci)
[Molecular Formula]

C24H27NO4
[MDL Number]

MFCD01677262
[MOL File]

6879-02-3.mol
[Molecular Weight]

393.48
Chemical PropertiesBack Directory
[Melting point ]

220 °C
[Boiling point ]

559.9±45.0 °C(Predicted)
[density ]

1.26±0.1 g/cm3(Predicted)
[pka]

7.62±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

Tylocrebrine is a compound with anticancer activity. Its clinical research was interrupted due to toxicity issues. By making it into targeted nanoparticles, its inhibitory index can be improved, the killing effect on tumor cells can be enhanced and brain penetration can be reduced.
[References]

[1] Reformulating Tylocrebrine in Epidermal Growth Factor Receptor Targeted Polymeric Nanoparticles Improves Its Therapeutic Index DOI:10.1021/acs.molpharmaceut.5b00173
6879-02-3 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
Website: https://www.targetmol.com/
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
Company Name: Lanospharma Laboratories Co.,Ltd  
Tel: 13440048448
Website: www.lanospharma.com
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