| Identification | Back Directory | [Name]
(+)-HIMBACINE | [CAS]
6879-74-9 | [Synonyms]
HIMBACINE
(+)-HIMBACINE
(+)-Himbacine,98%
(3s-(3-alpha,3a-alpha,4-beta(1e,2(2r*,6s*)),4a-beta,8a-alpha,9a-yl)-3-methyl
naphtho(2,3-c)furan-1(3h)-one,decahydro-4-(2-(1,6-dimethyl-2-piperidinyl)ethen
(3s,3ar,4r,4as,8ar,9as)-4-[(1e)-2-[(2r,6s)-1,6-dimethyl-2-piperdinyl]ethenyl]decahydro-3-methyl-naphtho[2,3-c]furan-1(3h)-one
(3S)-4α-[(E)-2-[(2R,6S)-1,6-Dimethyl-2-piperidinyl]vinyl]-3aβ,4,4aα,5,6,7,8,8aβ,9,9aβ-decahydro-3-methylnaphtho[2,3-c]furan-1(3H)-one
(3S)-3β-Methyl-4α-[(E)-2-[(2R)-1,6α-dimethyl-2β-piperidinyl]vinyl]-1,3,3aβ,4,4aα,5,6,7,8,8aβ,9,9aβ-dodecahydronaphtho[2,3-c]furan-1-one
(3S)-3β-Methyl-4α-[(E)-2-[(2R,6S)-1,6-dimethyl-2-piperidinyl]ethenyl]-1,3,3aβ,4,4aα,5,6,7,8,8aβ,9,9aβ-dodecahydronaphtho[2,3-c]furan-1-one | [EINECS(EC#)]
205-938-6 | [Molecular Formula]
C22H35NO2 | [MDL Number]
MFCD00274559 | [MOL File]
6879-74-9.mol | [Molecular Weight]
345.52 |
| Chemical Properties | Back Directory | [Appearance]
white to off-white powder | [Melting point ]
130-136 °C
| [Boiling point ]
480.42°C (rough estimate) | [density ]
1.0315 (rough estimate) | [refractive index ]
1.5614 (estimate) | [solubility ]
ethanol: 50 mg/mL
| [form ]
powder
| [color ]
off-white
|
| Hazard Information | Back Directory | [Chemical Properties]
white to off-white powder | [Definition]
ChEBI: A piperidine alkaloid that is decahydronaphtho[2,3-c]furan-1(3H)-one substituted by a methyl group at position 3 and a 2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethenyl group at position 4. It
as been isolated from the bark of Australian magnolias. | [Uses]
Himbacine is an alkaloid muscarinic receptor antagonist. | [in vivo]
Himbacine (1-4 mg/kg; i.v.) decreases both mean blood pressure and heart rate in cats[1]. | Animal Model: | 2-3 kg Cats[1] | | Dosage: | 1-4 mg/kg | | Administration: | I.v. | | Result: | Decreased in both mean blood pressure and heart rate with the hypotensive effect varied between 2 and 10 min. The fall in heart rate was relatively prolonged, usually 10 min or more. |
|
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Enzo Biochem Inc
|
| Tel: |
Enzo Biochem Inc. 13797054060 |
| Website: |
www.enzo.com |
|