| Identification | Back Directory | [Name]
Sophoramine | [CAS]
6882-66-2 | [Synonyms]
Sophoramine
SOPHORAMINE96%
11,12,13,14-Tetradehydromatridin-15-one
Matridin-15-one, 11,12,13,14-tetradehydro-
(4(1)S,7aS,13bS)-2,3,5,6,7,7a,8,13b-octahydro-1H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10(4(1)H)-one
1H,5H,10H-Dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one, 2,3,6,7,7a,8,13b,13c-octahydro-, (7aS,13bS,13cS)- | [Molecular Formula]
C15H20N2O | [MDL Number]
MFCD01632128 | [MOL File]
6882-66-2.mol | [Molecular Weight]
244.336 |
| Hazard Information | Back Directory | [Description]
An alkaloid present in Sophora alopecuroides, the base possesses the tetracyclic
structure characteristic of the Sophora alkaloids. It is 1aevorotatory with [α]D -
90.85° or - 98° (EtOH). It yields a series of well crystalline salts and derivatives
including the hydrochloride, m.p. 247-8° (dec.); hydriodide, m.p. 294-6°C;
aurichloride, m.p. 183-4°C (dec.); p1atinich1oride, m.p. 245-7°C (dec.); picrate,
m.p. 229-231°C (dec.) and the picrolonate, m.p. 173-5°C (dec.). | [Uses]
Sophoramine is a quinolizidine alkaloid isolated from traditional Chinese herbal drugssuch as Sophora flavescens Ait. (Kushen), S. alopecuroides L. (Kudouzi or Kugancao) and S. tonkinensis Gapnep (Shandougen). | [Definition]
ChEBI: Sophoramine is a naphthyridine derivative. | [References]
Orekhov., Chern. Zentr., II, 2215 (1935)
Orekhov, Proskurnina, Konovalova., Ber., 68,431 (1935)
Proskurnina, Kuzovkov., Dokl. Akad. Nauk SSSR, 91, 1145 (1953)
Okuda et al., Chern. & Ind., 1326 (1962) |
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