| Identification | Back Directory | [Name]
Ceftolozane Sulfate | [CAS]
689293-68-3 | [Synonyms]
CXA-101
JNYY93683
Ceftolozare
[2H6]-Ceftolozane
Ceftolozane Sulfate
Ceftolozane (CXA-101) TFA salt
CeftolozaneQ: What is
Ceftolozane Q: What is the CAS Number of
Ceftolozane | [Molecular Formula]
C23H30N12O8S2 | [MDL Number]
MFCD30747942 | [MOL File]
689293-68-3.mol | [Molecular Weight]
666.69 |
| Hazard Information | Back Directory | [Uses]
Ceftolozane Sulfate is an antibiotic belonging to the class of Cephalosporin (Cephalosporin C Zinc Salt, C258750). | [Definition]
ChEBI: Ceftolozane is a fifth-generation cephalosporin antibiotic having (5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl and [(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino side groups located at positions 3 and 7 respectively; developed for the treatment of infections with gram-negative bacteria that have become resistant to conventional antibiotics. It is a cephalosporin and a member of thiadiazoles. | [in vivo]
Ceftolozane (25 mg/kg) reveals a pharmacokinetic profil with a half-time of 11.6 min and a clearance of 25.2 μg/mL in infected neutropenic mice[1]. |
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