| Identification | Back Directory | [Name]
Mulberrofuran A | [CAS]
68978-04-1 | [Synonyms]
Mulberrofuran A
2-[2-[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]-5-hydroxy-3-methoxyphenyl]-6-benzofuranol
6-Benzofuranol, 2-[2-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-5-hydroxy-3-methoxyphenyl]-
2-{2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-5-hydroxy-3-methoxyphenyl}-1-benzofuran-6-ol | [Molecular Formula]
C25H28O4 | [MOL File]
68978-04-1.mol | [Molecular Weight]
392.49 |
| Hazard Information | Back Directory | [Description]
Mulberrofuran A can inhibit the formations of 12-hydroxy-, 8, 10-heptadecatrienoic acid (HHT) and thromboxane B2, but it can increase the formation of 12-hydroxy-5, 8, 10, 14-eicosatetraenoic acid (12-HETE). | [Uses]
Mulberrofuran A is a natural product, that can be isolated from the root bark of mulberry tree. Mulberrofuran A inhibits the formations of 12-hydroxy-,8,10-heptadecatrienoic acid (HHT) and thromboxane B2 (cyclooxygenase products), but it increases the formation of 12-hydroxy-5,8,10,14-eicosatetraenoic acid (12-HETE) (12-lipoxygenase product)[1]. | [Definition]
ChEBI: Mulberrofuran A is a member of 1-benzofurans. | [target]
COX | [References]
[1] Kimura Y, et al. Effects of flavonoids and related compounds from mulberry tree on arachidonate metabolism in rat platelet homogenates. Chem Pharm Bull (Tokyo). 1986 Mar;34(3):1223-7. DOI:10.1248/cpb.34.1223 |
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