| Identification | Back Directory | [Name]
2',3'-O-Isopropylidene-4'-alpha-azido-uridine | [CAS]
690271-27-3 | [Synonyms]
2',3'-O-Isopropylidene-4'-alpha-azido-uridine
2’,3’-Di-O-isopropylidene-4’-α-C-azidouridine
4'-C-Azido-2',3'-O-(1-methylethylidene)uridine
2',3'-Di-O-isopropylidene-4'-alpha-azido-uridine
Uridine, 4'-C-azido-2',3'-O-(1-Methylethylidene)-
2’,3’-Di-O-isopropylidene-4’-alpha-C-azidouridine
4'-azido-2',3'-O-isopropylidenyluridine-4'-azido-2',3'-O-isopropylidenyluridine | [Molecular Formula]
C12H15N5O6 | [MDL Number]
MFCD22666297 | [MOL File]
690271-27-3.mol | [Molecular Weight]
325.277 |
| Hazard Information | Back Directory | [Uses]
2’,3’-Di-O-isopropylidene-4’-alpha-C-azidouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1]. 2’,3’-Di-O-isopropylidene-4’-alpha-C-azidouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [References]
[1] Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25. DOI:10.1016/s0165-6147(99)01298-5 |
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