| Identification | Back Directory | [Name]
Moracin D | [CAS]
69120-07-6 | [Synonyms]
Moracin D
product/154913
2H-1-Benzopyran-5-ol, 7-(6-hydroxy-2-benzofuranyl)-2,2-dimethyl- | [Molecular Formula]
C19H16O4 | [MDL Number]
MFCD25973126 | [MOL File]
69120-07-6.mol | [Molecular Weight]
308.33 |
| Chemical Properties | Back Directory | [Boiling point ]
406.9±45.0 °C(Predicted) | [density ]
1.295±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
9.06±0.40(Predicted) |
| Hazard Information | Back Directory | [Uses]
Moracin D is a flavonoid that can be isolated from Morus alba. Moracin D induces cell apoptosis and shows hypoglycemic, antiadipogenic, antifungal and antitumor effects. Moracin D can be used for fungal infection and breast cancer research[1][2][3]. | [Definition]
ChEBI: Moracin D is a member of benzofurans. | [target]
COX | c-Myc | TNF-α | Antifection | [References]
[1] Yoon JS, et al. Moracin D induces apoptosis in prostate cancer cells via activation of PPAR gamma/PKC delta and inhibition of PKC alpha. Phytother Res. 2021 Dec;35(12):6944-6953. DOI:10.1002/ptr.7313
[2] Takasugi Mitsuo, et al. MORACIN C AND D, NEW PHYTOALEXINS FROM DISEASED MULBERRY. CSJ Journals. 1978, Vol.7, No.11.
[3] Hwang SM, et al. Inhibition of Wnt3a/FOXM1/β-Catenin Axis and Activation of GSK3β and Caspases are Critically Involved in Apoptotic Effect of Moracin D in Breast Cancers. Int J Mol Sci. 2018 Sep 10;19(9):2681. DOI:10.3390/ijms19092681 |
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