| Identification | Back Directory | [Name]
2-(prop-2-en-1-yl)-6-{[(1-propyl-1H-benzimidazol-2-yl)amino]methyl}phenol | [CAS]
692269-09-3 | [Synonyms]
CM10
2-(prop-2-en-1-yl)-6-{[(1-propyl-1H-benzimidazol-2-yl)amino]methyl}phenol
Phenol, 2-(2-propen-1-yl)-6-[[(1-propyl-1H-benzimidazol-2-yl)amino]methyl]- | [Molecular Formula]
C20H23N3O | [MDL Number]
MFCD03683082 | [MOL File]
692269-09-3.mol | [Molecular Weight]
321.42 |
| Chemical Properties | Back Directory | [Boiling point ]
512.4±52.0 °C(Predicted) | [density ]
1.12±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [solubility ]
DMSO: 125 mg/mL (388.90 mM) | [form ]
A solid | [pka]
10.10±0.35(Predicted) | [color ]
Light green to green |
| Hazard Information | Back Directory | [Uses]
CM010 is a potent and selective aldehyde dehydrogenase 1A (ALDH1A) family inhibitor, with IC50s of 1700, 740, and 640 nM for ALDH1A1, ALDH1A2, and ALDH1A3, respectively. CM010 does not inhibit any of the other ALDH family members. CM010 can regulate metabolism and has anti-cancer activity[1]. | [IC 50]
ALDH1 | [storage]
Store at -20°C | [References]
[1] Chefetz I, et al. A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells. Cell Rep. 2019 Mar 12;26(11):3061-3075.e6. DOI:10.1016/j.celrep.2019.02.032 |
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| Company Name: |
InvivoChem
|
| Telephone: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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